Mouse Anti-RAB5A Monoclonal Antibody (CBP2751)

Product Overview

Description

Rab5a belongs to the Rab GTPases family proteins, which play roles in endocytosis, exocytosis, and vesicular transportation. Rab family proteins were recently reported to play important roles in human cancer progression. Rab5a was reported to be overexpressed in breast and ovarian cancers and associated with proliferation and invasion.

Expression Host

Mammalian cells

Immunogen

RAB5A fusion protein Ag16781

Species Reactivity

Human; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2751

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1200 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Rab5

Official Name

RAB5A

Full Name

RAB5A, member RAS oncogene family

Alternative Names

RAB5; RAB5A; Ras related protein Rab 5A

Gene ID

5868(Human); 271457(Mouse); 64633(Rat)

Uniprot ID

P20339(Human); Q9CQD1(Mouse); M0RC99(Rat)

References

1. He, R., Wang, M., Zhao, C., Shen, M., Yu, Y., He, L.,... & Pan, S. (2019). TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells. Journal of Experimental & Clinical Cancer Research, 38(1), 1-14. 2. Meng, K., Zhuang, X., Peng, T., Hu, S., Yang, J., Wang, Z.,... & Liu, X. (2020). Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium. Communications Biology, 3(1), 1-13.

Publications