Mouse Anti-ADAM10 Monoclonal Antibody (CBP2815)

Product Overview

Description

ADAM10 is widely expressed in the brain, the spinal cord, and the visual system during development.MW of premature ADAM10 is 90 kDa and mature ADAM10 is 60-70 kDa.

Expression Host

Mammalian cells

Immunogen

ADAM10 fusion protein Ag23062

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2815

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

ADAM10

Official Name

ADAM10

Full Name

ADAM metallopeptidase domain 10

Alternative Names

A disintegrin and metalloprotease domain 10;
A disintegrin and metalloproteinase domain 10;
AD 10;
AD10;
AD18;
ADA10_HUMAN;
ADAM 10;
ADAM metallopeptidase domain 10;
ADAM10;
CD 156c;
CD156c;
CD156c antigen;

Gene ID

102(Human); 11487(Mouse); 29650(Rat)

Uniprot ID

O14672(Human); O35598(Mouse); Q10743(Rat)

References

1. Hicks, D. A., Jones, A. C., Pickering-Brown, S. M., & Hooper, N. M. (2020). The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43. Bioscience Reports, 40(4). 2. Chai, F. N., Ma, W. Y., Zhang, J., Xu, H. S., Li, Y. F., Zhou, Q. D.,... & Ye, X. L. (2018). Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122. Biomedicine & Pharmacotherapy, 103, 1002-1011. 3. Zhang, Z., Xu, L., He, L., Wang, J., Shi, X., Li, Z.,... & Qu, X. (2020). MiR-891a-5p as a prognostic marker and therapeutic target for hormone receptor-positive breast cancer. Journal of Cancer, 11(13), 3771.

Publications