Mouse Anti-JAG1 Monoclonal Antibody (CBP2866)

Product Overview

Description

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis.

Expression Host

Mammalian cells

Immunogen

Jagged1 fusion protein Ag11891

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgA

Clone Number

CBP2866

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD339

Official Name

JAG1

Full Name

Jagged 1

Alternative Names

AGS; AHD; AWS; CD339; HJ1; JAG1; jagged 1 (Alagille syndrome); Jagged1; JAGL1; Protein jagged 1

References

1. Gong, F., Chai, W., Wang, J., Cheng, H., Shi, Y., Cui, L., & Jia, G. (2020). miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway. Acta histochemica, 151527. 2. Gong, F., Cheng, H., Shi, Y., Cui, L., & Jia, G. (2020). LncRNA TDRG1/miR-214-5p axis affects preeclampsia by modulating trophoblast cells. Cell biochemistry and function, 38(4), 352-361.

Publications