Mouse Anti-TBK1 Monoclonal Antibody (CBP2928)

Product Overview

Description

TBK1 is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the 'noncanonical IkB kinases' (IKKs) recognized for its critical role in regulating type I IFN production. And TBK1 is an important player in yet another critical cellular function, autophagy.

Expression Host

Mammalian cells

Immunogen

TBK1 fusion protein Ag28894

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2928

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

TBK1

Official Name

TBK1

Full Name

TANK-binding kinase 1

Alternative Names

FLJ11330; NAK; NF kappa B activating kinase; T2K; TANK binding kinase 1; TBK1

Gene ID

29110(Human); 56480(Mouse); 299827(Rat)

Uniprot ID

Q9UHD2(Human); Q9WUN2(Mouse)

References

1. Peng, Y., Zhuang, J., Ying, G., Zeng, H., Zhou, H., Cao, Y.,... & Li, J. (2020). Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage. Journal of neuroinflammation, 17(1), 1-20. 2. Li, M., & Shu, H. B. (2020). Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response. Protein & Cell.

Publications