Product
Mouse Anti-DBN1 Monoclonal Antibody (CBP2978)
[CAT#: NAB20102056CR]
Mouse Monoclonal (1A12H1) to DBN1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat; Porcine
- Applications:
- IHC; WB; ELISA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients.
Expression Host
Mammalian cells
Immunogen
Drebrin fusion protein Ag22635
Species Reactivity
Human; Mouse; Rat; Porcine
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP2978
Applications
IHC; WB; ELISA
Application Notes
IHC : 1:20-1:200; WB : 1:500-1:1000
Research Areas
Neurogenesis
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
500 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Drebrin
Official Name
DBN1
Full Name
Drebrin 1
Alternative Names
D0S117E;
DBN 1;
DBN1;
Developmentally regulated brain protein;
Developmentally-regulated brain protein;
DKFZp434D064;
DREB_HUMAN;
Drebrin 1;
Drebrin;
Drebrin E;
DBN 1;
DBN1;
Developmentally regulated brain protein;
Developmentally-regulated brain protein;
DKFZp434D064;
DREB_HUMAN;
Drebrin 1;
Drebrin;
Drebrin E;
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
