Mouse Anti-Human PARK2 Monoclonal Antibody (CBP3727)
[CAT#: NAB201284LS]
Anti-PARK2 Monoclonal Antibody [HRP]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
PAK2 (p21-activated kinase 2) is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, and proliferation. It acts as the downstream effector of the small GTPases CDC42 and RAC1. PAK2 stimulates cell survival and cell growth, and knockdown of PAK2 induces cell cycle arrest. PAK2 is also implicated in the immune system.
Immunogen
Recombinant fragment of human PAK2 (a.a. 4-223) protein.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3727
Applications
WB
Application Notes
WB (0.1-0.5 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Product Properties
Form
Liquid
Formulation
50% glycerol in aqueous buffered solutions with preservatives.
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon receipt, the antibody solution should be stored undiluted at-20°C, and protected from prolonged exposure to light.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Fuchsova B, et al. 2016. Neuroscience. 333:331
2. O'Hagan KL, et al. 2017. Sci Rep. 7:17097
3. Koo KH and Kwon H. 2018. Cell Death Dis. 9:77
2. O'Hagan KL, et al. 2017. Sci Rep. 7:17097
3. Koo KH and Kwon H. 2018. Cell Death Dis. 9:77
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
Neural Genes
Kits
For Research Use Only. Not For Clinical Use.
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