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Creative Biolabs
Product

Mouse Anti-Human CD49C Monoclonal Antibody (CBP3880)

[CAT#: NAB2012441LS]

Anti-CD49C Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC-F; FC; IP

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Product Overview

Description

CD49c is a 150 kD α integrin chain known as α3 integrin or VLA-3 α chain. It is a type I transmembrane glycoprotein which is proteolytically cleaved into two disulfide linked fragments of 125 kD and 30 kD. CD49c forms a heterodimer with integrin β1 (α3β1, CD49c/CD29, VLA-3) and is expressed by many types of adhesion cells.

Immunogen

The monoclonal antibody was generated against human HT1080 cells.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3880

Applications

IHC-F; FC; IP

Application Notes

IHC (1.0-5.0 µg/mL); FCM (1.0-10.0 µg/mL); ICC (1.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD49C

Official Name

ITGA3

Full Name

Integrin alpha 3

Alternative Names

ITGA3; CD49C; GAP-B3; GAPB3; ILNEB; MSK18; VCA-2; VL3A; VLA3a; FRP-2; integrin subunit alpha 3

Gene ID

3675 (Human); 16400 (Mouse)

Uniprot ID

P26006 (Human); Q62470 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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