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Creative Biolabs

Anti-CD88 Monoclonal Antibody (CBP3960)

[CAT#: NAB2012890LS]

Anti-CD88 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; African green monkey; Baboon
Applications:
FC

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Product Overview

Description

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. D86 has been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Immunogen

Recombinant peptide huC5aR N-terminal-NT (Asp15-Asp27)

Species Reactivity

Human; African green monkey; Baboon

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3960

Applications

FC

Application Notes

FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD88

Official Name

C5AR1

Full Name

Complement component 5a receptor 1

Alternative Names

GFAP

Gene ID

728 (Human); 12273 (Mouse)
Publications

Publications (0)

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