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Creative Biolabs

Mouse Anti-Rat CD62P Monoclonal Antibody (CBP3977)

[CAT#: NAB2012919LS]

Anti-CD62P Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
FC

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Product Overview

Description

CD62P is a 140 kD type I transmembrane glycoprotein, also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells. CD62P is primarily stored in secretory α-granules in platelets and Weibel-Palade bodies in endothelial cells, and is rapidly relocated to the plasma membrane upon activation. A primary function of CD62P is cell adhesion during neutrophil rolling, and platelet-neutrophil and platelet-monocyte interactions.

Immunogen

Thrombin activated rat platelets

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3977

Applications

FC

Application Notes

FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 101 µL of whole blood)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.2 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD62P

Official Name

SELP

Full Name

P-selectin

Alternative Names

SELP

Uniprot ID

P16109 (Human); Q01102 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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