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Creative Biolabs

NeuroMab™ Mouse Anti-Human HDAC1 Monoclonal Antibody (CBP3992)

[CAT#: NAB2012989LS]

Anti-HDAC1 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IP; IHC-P; WB

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Product Overview

Description

HDAC1 is a member of class I histone deacetylase (HDACs) family, which modulates the chromatin structure by removing acetyl groups (deacetylation) from the side chain of lysine residues on the N-terminal region of core histones (H2A, H2B, H3 and H4). Generally, histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle programming and developmental process.

Immunogen

This monoclonal antibody was raised against a peptide sequence derived from the C-terminus of the human HDAC1 protein.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP3992

Applications

IP; IHC-P; WB

Application Notes

IP (1:100-1:350); IHC-P (1:50- 1:100); WB(1:1000-1:4000)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

HDAC1

Official Name

HDAC1

Full Name

Histone deacetylase 1

Alternative Names

HDAC1

Uniprot ID

Q13547 (Human); O09106 (Mouse)
Publications

Publications (0)

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