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Creative Biolabs

Rabbit Anti-Integrin Beta 1 Monoclonal Antibody (CBP4051)

[CAT#: NAB2007FY1190]

Rabbit Monoclonal (AB009) to Integrin Beta 1

Host Species:
Rabbit
Species Reactivity:
Human
Applications:
WB; IHC

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Product Overview

Description

Integrin α-V/β-1 is the receptor for vitronectin. Beta-1 integrin can recognize the sequence R-G-D in a variety of ligands. Isoform 2 interferes with isoform 1, resulting in a significant negative effect on cell adhesion and migration (in vitro). When combined with alpha-7/beta-1 integrin, it regulates cell adhesion and laminin matrix deposition. Participate in promoting endothelial cell movement and angiogenesis. The matrix assembly process mediated by fibronectin fibril forming cells participates in the compaction of osteoblasts and forms mineralized bone nodules. It may be involved in the up-regulation of kinase (such as PKC) activity by binding to KRT1.

Immunogen

A peptide corresponding to residues in human CD29 (integrin beta-1).

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Rabbit

Isotype

IgG

Clone Number

CBP4051

Applications

WB; IHC

Application Notes

WB: 1:2000-1:4000
IHC: 1:100-1:200

Conjugation

Unconjugated
Product Properties

Form

colorless liquid

Formulation

In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Preservatives

Yes

Purification

Affinity purified

Shipping

Gel Pack

Storage

-20°C

Handling Advice

The antibody solution should be gently mixed before use.
Target

Target

CD29

Official Name

ITGB1

Full Name

Integrin beta-1

Alternative Names

ITGB1; CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB; integrin subunit beta 1

Gene ID

3688(Human); 16412(Mouse)

Uniprot ID

P05556(Human); P09055(Mouse)
Publications

Publications (0)

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