Rabbit Anti-CD137 Monoclonal Antibody (CBP4067)

[CAT#: NAB2007FY1340]

Rabbit Monoclonal (AB016) to CD137

Host Species:: Rabbit

Species Reactivity:: Human

Applications:: WB; IHC

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Product Overview

Description

The protein encoded by this gene is a member of the TNF receptor superfamily. The receptor helps the clonal expansion, survival and development of T cells. It can also induce the proliferation of peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 activation, and regulate CD28 co-stimulation to promote Th1 cell response. The expression of this receptor is induced by lymphocyte activation. The TRAF adaptor protein has been shown to bind to this receptor and transduce the signal leading to NF-κB activation.

Immunogen

Recombinant fragment of human CD137 protein (aa 19-188)

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Rabbit

Isotype

IgG

Clone Number

CBP4067

Applications

WB; IHC

Application Notes

WB: 1-2 µg/mL
IHC: 1-2 µg/mL

Conjugation

Unconjugated

Product Properties

Form

colorless liquid

Formulation

PBS

Preservatives

BSA free

Purification

Protein A/G purified

Shipping

Gel Pack

Storage

-20°C

Handling Advice

The antibody solution should be gently mixed before use.

Target

TNFRSF9

Official Name

TNFRSF9

Full Name

TNFRSF9 Gene(Protein Coding) TNF Receptor Superfamily Member 9

Alternative Names

TNF Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; CD137; ILA; Interleukin-Activated Receptor; Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily; Member 9