Mouse Anti-Neurofilament Light Chain Peptide, NF-L. Monoclonal Antibody (CBP6677)
[CAT#: NAB2007FY1538]
Mouse Monoclonal to Neurofilament Light Chain Peptide, NF-L.
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat; Mouse; Cow; Porcine
- Applications:
- WB; IF; IHC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Neurofilaments are 10nm or intermediate filament proteins that are specifically found in neurons. They are mainly composed of three main proteins called NF-L, NF-M and NF-H, but they may also include other filament proteins. The main function of nerve filaments may be to control the diameter of large axons (1). NF-L is a neurofilament light or low molecular weight peptide. It runs on a 68-70kDa SDS-PAGE gel. There are some differences between different species. NF-L antibodies (such as MCA-6H112) can be used to identify neuronal cells and their processes in cell culture and sectioning materials. NF-L antibody can also be used to visualize the accumulation of neurofilaments that is seen in many neurological diseases, such as Lou Gehrig's disease (ALS), giant axon neuropathy, Charcot-Marie Tooth disease, etc. (2-4).
Immunogen
The C-terminal peptide of human NF-L protein, GEEEDTKESEEEEKKEESAGEEQVAKKKD, with an N-terminal C for coupling to KLH
Species Reactivity
Human; Rat; Mouse; Cow; Porcine
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP6677
Applications
WB; IF; IHC
Application Notes
WB: 1:5,000 IF/ICC and IHC: 1:1,000
Product Properties
Form
Liquid
Formulation
50% PBS, 50% glycerol
Preservatives
5mM NaN3
Concentration
1 mg/ml
Shipping
Gel Pack
Storage
Store at 4°C for short term, for longer term at -20°C.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Target
Neurofilament L
Official Name
NEFL
Full Name
Neurofilament light polypeptide
Alternative Names
NEFL; CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110; neurofilament; light polypeptide; neurofilament light; CMTDIG
Publications
Publications (0)
Neural Genes
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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