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Creative Biolabs
Product

Mouse Anti-GFAP Monoclonal Antibody (CBP6781)

[CAT#: NAB2007FY1730]

Astrocytes

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IHC; WB

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Product Overview

Description

Neuroinflammation is locally produced in the central nervous system through phenotypic changes of different non-neuronal cell types (such as microglia, oligodendrocytes, and astrocytes) in the brain, leading to different cytokines and chemokines The release of C, eventually recruits and infiltrates peripheral blood cells, mainly T-and B cells, into the brain parenchyma. This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Epitope

Binds to an located within the peptide sequence PVQTFSNLQIRETSL

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6781

Applications

IHC; WB

Application Notes

IHC: 1:5000-1:10000
WB: 1 µg/ml

Marker

Glial Cell Markers; Astrocyte Markers
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

1 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

GFAP

Official Name

GFAP

Full Name

Glial Fibrillary Acidic Protein

Alternative Names

Glial Fibrillary Acidic Protein; Intermediate Filament Protein; ALXDRD

Gene ID

2670(Human); 14580(Mouse); 24387(Rat)

Uniprot ID

P14136(Human); P03995(Mouse); P47819(Rat)
Publications

Publications (0)

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