NeuroMab™ Anti-Kv4.2 potassium channel (CBP8326)

Product Overview

Immunogen

Synthetic peptide amino acids 209-225 (CGSSPGHIKELPSGERY, extracellular S1-S2 loop, where third Ser was substituted in place of a Cys for peptide conjugation purposes) of human Kv4.2 (Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2, Kcnd2, Kiaa1044, MNCb-7013, RK5 and Shal1, accession number Q9NZV8)
Rat: 100% identity (17/17 amino acids identical)
Mouse: 100% identity (17/17 amino acids identical)
>75% identity with Kv4.3

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8326

Applications

WB; IHC; IP; ICC

Application Notes

Does not cross-react with Kv4.3

Research Areas

K+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

KCND2

Official Name

KCND2

Full Name

Kv4.2 K+ channel (external)

Alternative Names

KCND2; KV4.2; RK5; potassium voltage-gated channel subfamily D member 2

Uniprot ID

Q9NZV8

Product Pictures

Fig. 1 Immunoblot against crude brain membranes from adult rat (RBM) and wild-type (MBM-WT) and Kv4.2 knockout (MBM-Kv4.2-KO) mice probed with K57/1 (left) or K89/41 (right) TC supe.

Fig. 2 Immunoblot against crude C. elegans worm extracts and RBM.

Fig. 3 Immunoblot against crude membranes from whole mouse (MBM) or rat (RBM) brain and from human cerebellum [HBM(Cb)], cerebral cortex [HBM(Cx)] or hippocampus [HBM(H)] and probed with K57/1 (left) or N52A/42 loading control (right) TC supe.