NoGeneST™ Anti-mTOR Aptamer, amTOR aptamer

Name: NoGeneST™ Anti-mTOR Aptamer, amTOR aptamer
SKU: NRYF-0625-HZ98
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ98]

Aptamer designed to specifically recognize mTOR, a central kinase that regulates cell growth, proliferation, and metabolism.

Target:: mTOR

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Product Overview

Relevant Diseases

Epilepsy

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

mTOR

Full Name

Serine/Threonine-Protein Kinase mTOR

Alternative Names

FRAP1; RAFT1; Mechanistic target of rapamycin

Gene ID

2475

Uniprot ID

P42345

Target Overview

The mechanistic target of rapamycin (mTOR) is a crucial serine/threonine kinase that serves as a central regulator of cell metabolism, growth, proliferation, and survival. It integrates signals from various upstream pathways, including nutrients, energy levels, and growth factors, to control key cellular activities like protein synthesis and autophagy. mTOR forms the catalytic core of two distinct protein complexes, mTORC1 and mTORC2, each with different downstream targets and functions. Because its signaling pathway is frequently hyperactive in many human diseases, most notably cancer, mTOR is a major therapeutic target.

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