NoGeneST™ Anti-Neurexin Aptamer, aNeurexin aptamer

Name: NoGeneST™ Anti-Neurexin Aptamer, aNeurexin aptamer
SKU: NRYF-0625-HZ113
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ113]

Aptamer designed to specifically recognize Neurexin, a family of presynaptic cell adhesion molecules crucial for synapse function and implicated in autism.

Target:: Neurexin

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Product Overview

Relevant Diseases

Autism Spectrum Disorder

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

Neurexin

Full Name

Neurexin-1

Alternative Names

NRXN1

Gene ID

9378

Uniprot ID

Q9ULB1

Target Overview

Neurexins are a family of presynaptic cell adhesion molecules (encoded by the NRXN1, NRXN2, and NRXN3 genes) that are essential for the proper formation and function of synapses in the brain. They act as key organizers at the synapse by binding to a variety of postsynaptic partners, most notably Neuroligins, to form a trans-synaptic bridge. This interaction is critical for specifying synaptic properties and ensuring correct neurotransmission. Due to their fundamental role in building and maintaining neural circuits, genetic disruptions of Neurexin genes are strongly associated with a range of neurodevelopmental disorders, including Autism Spectrum Disorder (ASD) and schizophrenia.

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