NoGeneST™ LRRK2-ASO, Antisense Oligonucleotide
[CAT#: NRYF-0625-XY73]
- Target:
- LRRK2
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
LRRK2-ASO is an antisense oligonucleotide designed to decrease LRRK2 kinase activity and alleviating LRRK2-associated neuronal dysfunction in PD.
Species
Human
Applications
Reduces LRRK2 expression to study its role in neuronal autophagy, mitochondrial dysfunction, and dopaminergic neurodegeneration in Parkinson's disease (PD). Enables preclinical evaluation of LRRK2 inhibition for neuroprotection. Optimized for in vivo PD models (e.g., α-synuclein transgenic mice).
Relevant Diseases
Parkinson's disease
Properties
Appearance
Solid
Shipping
Room temperature
Storage
Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).
Research Use Only
For research use only.
Target Details
Target
LRRK2
Official Name
LRRK2
Full Name
Leucine-rich repeat kinase 2
Alternative Names
LRRK2; AURA17; DARDARIN; PARK8; RIPK7; ROCO2; leucine-rich repeat kinase 2; leucine rich repeat kinase 2
Publications
Publications (0)
Neural Genes
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
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