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Creative Biolabs
Product

KCC2 Stable HEK293 Cell Line

[CAT#: NCL-2105-P315-AM]

These cells can be used for disease modeling, drug screening and toxicology testing.

Species:
Human

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Product Overview

Description

KCC2 Stable The HEK293 cell line at Creative Biolabs stably overexpresses the neuron-specific K-Cl cotransporter isoform KCC2. This cell line is suitable for the central nervous system to study the potential role of KCC2 in ion homeostasis.

Species

Human
Properties

Growth Pattern

Adherent

Morphology

Polygonal

Seeding Density

30,000 - 50,000 cells/cm2, Split ratio: 1:2 or 1:3

Population Doubling Time

30 - 40 hours

Freeze Medium

90% FBS+10% DMSO

Tissue Source

Renal

Cell Purity

>95%

Cell Viability

>90%

Mycoplasma Testing

Negative

Sterility Testing

The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Genetic Stability Testing

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

Shipping

Frozen on dry ice

Storage

Liquid nitrogen immediately upon delivery

Research Use Only

For research use only

Quality Control

1) Use the 86Rb influx test to screen cell lines to determine the KCC2 expressed on the cell surface; 2) Western blot to detect protein expression
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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