NeuroMab™ Mouse Anti-Myelin Basic Protein Monoclonal Antibody (Clone L-S-287)
[CAT#: NAB2010533LS]
Anti-Myelin Basic Protein Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC-P; WB; ICC; IHC-Fr
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Myelin basic protein (MBP) is a protein involved in the myelination of nerves in the central nervous system (CNS). MBP functions to maintain the correct structure of myelin, through its interaction with the lipids in the myelin membrane. The myelin sheath is made up of MBP and lipids, and acts as an insulator to increase the velocity of axonal impulse conduction. MBP plays a central role in the demyelinating disease multiple sclerosis (MS). A hallmark of the disease is the loss of the myelin sheath surrounding nerves, thought to be induced by antibodies against MBP.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
L-S-287
Applications
IHC-P; WB; ICC; IHC-Fr
Application Notes
IHC (1.0 - 5.0 μg/mL); WB (1.0-5.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1789
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
Batch Dependent
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Neural Genes
Neural Antibodies
For Research Use Only. Not For Clinical Use.
