Mouse Anti-RELN Monoclonal Antibody (CBP1217)

Product Overview

Immunogen

Recombinant fusion protein, corresponding to amino acids 164-496 of Mouse Reelin

Species Reactivity

Mouse; Rat; Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, kappa

Clone Number

CBP1217

Applications

WB; IHC; ICC

Application Notes

Use at an assay dependent concentration

Research Areas

Neurogenesis

Pathways

Neurogenesis Signaling

Conjugation

Unconjugated

Product Properties

Formulation

Preservative: 0.1% Sodium azide
Constituents: 1.45% Sodium chloride, 0.242% Tris

Purification

Tissue culture supernatant

Purity

>95%

Shipping

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Storage

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes: avoid repeated freeze-thaw cycles.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Reelin

Official Name

RELN

Full Name

Reelin

Alternative Names

Reelin (RELN) is a secreted large extracellular matrix glycoprotein that can help regulate neuronal migration and localization in the developing brain by controlling cell-cell interactions. In addition to playing an important role in early development; Reelin also continues to play a role in the adult brain. It regulates synaptic plasticity by enhancing the induction and maintenance of long-term potentiation. It also stimulates the development of dendrites and dendritic spines and regulates the continued migration of neuroblasts produced in adult neurogenesis sites (such as the subventricular and subgranular regions). It is found not only in the brain; but also in the liver; thyroid; adrenal glands; fallopian tubes; and breasts; and is also low in a range of anatomical regions.