Mouse Anti-GAD2 Monoclonal Antibody (CBP1603)
[CAT#: NAB2007FY309]
Mouse Monoclonal [W0020] to GAD2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Mouse anti-human glutamate decarboxylase 2 antibody recognizes glutamate decarboxylase 2, also known as 65 kDa glutamate decarboxylase, GAD-65 or glutamate decarboxylase 65 kDa isoform.
Glutamate decarboxylase 2 is encoded by the GAD2 gene and is one of several forms of glutamate decarboxylase. Glutamate decarboxylase 2 is responsible for catalyzing the production of γ-aminobutyric acid from L-glutamic acid. The pathogenic effect of this enzyme has been identified in the human pancreas because it has been identified as an autoantibody and autoreactive T cell target in insulin-dependent diabetes. GAD2 may also play a role in stiff human syndrome. Alternative splicing results in multiple transcriptional variants encoding the same protein.
Glutamate decarboxylase 2 is encoded by the GAD2 gene and is one of several forms of glutamate decarboxylase. Glutamate decarboxylase 2 is responsible for catalyzing the production of γ-aminobutyric acid from L-glutamic acid. The pathogenic effect of this enzyme has been identified in the human pancreas because it has been identified as an autoantibody and autoreactive T cell target in insulin-dependent diabetes. GAD2 may also play a role in stiff human syndrome. Alternative splicing results in multiple transcriptional variants encoding the same protein.
Immunogen
Keyhole limpet haemocyanin (KLH) conjugated synthetic peptide sequence PGSGFWSFGSEDGSGDSEN corresponding to amino acids 4-22 within the N-terminal region of human glutamate decarboxylase 2.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1603
Applications
WB
Application Notes
WB (1/1000)
Research Areas
Growth and Development
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS
0.09% Sodium Azide
0.09% Sodium Azide
Purification
Mouse monoclonal antibody prepared by affinity chromatography on Protein G from tissue culture supernatant.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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