Product
Mouse Anti-Human LRRK2 Monoclonal Antibody (CBP2251)
[CAT#: NAB2010169LS]
Anti-LRRK2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Leucine-rich repeat kinase 2 (LRRK2), is a member of the leucine-rich repeat kinase family. This protein also functions as a GTPase. Proteins with leucine-rich regions play a role in protein-protein interactions and mediate assembly of the cell's structural framework (cytoskeleton). Mutations in LRRK2 genes have been associated with late-onset Parkinson's disease.
Immunogen
100-500 aa of human LRRK2.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG
Clone Number
CBP2251
Applications
WB
Application Notes
WB (1.0-2.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/ml
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Paisán-Ruíz C, et al. 2004. Neuron. 44(4):595-600.
2. Alegre-Abarrategui J, et al. 2009. Hum. Mol. Genet. 18(21):4022-34.
3. Gómez-Suaga P, et al. 2012. Hum. Mol. Genet. 21(3):511-25.
4. Orenstein SJ, et al. 2013. Nat. Neurosci. 16(4):394-406.
5. Cherra SJ, et al. 2013. Am. J. Pathol. 182(2):474-84.
2. Alegre-Abarrategui J, et al. 2009. Hum. Mol. Genet. 18(21):4022-34.
3. Gómez-Suaga P, et al. 2012. Hum. Mol. Genet. 21(3):511-25.
4. Orenstein SJ, et al. 2013. Nat. Neurosci. 16(4):394-406.
5. Cherra SJ, et al. 2013. Am. J. Pathol. 182(2):474-84.
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
For Research Use Only. Not For Clinical Use.
