Mouse Anti-SYP Monoclonal Antibody (CBP2636)

Product Overview

Description

Synaptophysin regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass. Synaptophysin is present in neuroendocrine cells and neurons that participate in synaptic transmission. Synaptophysin is a useful marker for identification of neuroendocrine cells and neoplasms.

Expression Host

Mammalian cells

Immunogen

Synaptophysin fusion protein Ag11803

Species Reactivity

Human; Mouse; Rat; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG3

Clone Number

CBP2636

Applications

IF; IHC; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neuron

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Synaptophysin

Official Name

SYP

Full Name

Synaptophysin

Alternative Names

Synaptophysin; SYP

Gene ID

6856(Human); 19027(Mouse); 366595(Rat)

Uniprot ID

Q16563(Human); O09117(Mouse)

References

1. Xin, D., Chu, X., Bai, X., Ma, W., Yuan, H., Qiu, J.,... & Liu, D. (2018). l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation. Brain, behavior, and immunity, 73, 222-234. 2. Liu, D., Bai, X., Ma, W., Xin, D., Chu, X., Yuan, H.,... & Wang, Z. (2020). Purmorphamine attenuates neuro-inflammation and synaptic impairments after hypoxic-ischemic injury in neonatal mice via Shh signaling. Frontiers in Pharmacology, 11, 204. 3. Yin, L., Hu, P., Shi, X., Qian, W., Zhau, H. E., Pandol, S. J.,... & Wang, R. (2020). cancer cell's neuroendocrine feature can be acquired through cell-cell fusion during cancer-neural stem cell interaction. Scientific reports, 10(1), 1-13.

Publications