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Creative Biolabs
Product

Mouse Anti-JUN Monoclonal Antibody (CBP2741)

[CAT#: NAB20101817CR]

Mouse Monoclonal (1G6B11) to JUN

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; ELISA

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Product Overview

Description

JUN is a basic leucine zipper (bZIP) transcription factor that recognizes and binds to a consensus heptamer motif of 5'-TGA[CG]TCA-3' in the enhancer region of target genes. JUN acts as either a homo- or heterodimer and binds to the DNA to regulate transcriptional activity, specifically promoting the activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon the stimulation of the cAMP signaling pathway.

Expression Host

Mammalian cells

Immunogen

JUN fusion protein Ag17639

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2741

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Growth and Development

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

JUN

Official Name

JUN

Full Name

Jun oncogene

Alternative Names

Activator protein 1;
AP 1;
AP-1;
AP1;
cJun;
Enhancer Binding Protein AP1;
Jun Activation Domain Binding Protein;
JUN;
Jun oncogene;

Gene ID

3725(Human); 16476(Mouse); 24516(Rat)

Uniprot ID

P05412(Human); P05627(Mouse); P17325(Rat)
Publications

Publications (0)

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