Mouse Anti-CASP3 Monoclonal Antibody (CBP2781)
[CAT#: NAB20101858CR]
Mouse Monoclonal (2G4B2) to CASP3
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IF; IHC; WB; ELISA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Caspases are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain.
Expression Host
Mammalian cells
Immunogen
Caspase 3/p17/p19 fusion protein Ag25029
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2781
Applications
IF; IHC; WB; ELISA
Application Notes
IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000
Research Areas
Neuroendocrinology
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Caspase-3
Official Name
CASP3
Full Name
Caspase 3, apoptosis-related cysteine peptidase
Alternative Names
Apopain; CASP 3; CASP3; Caspase 3; Caspase3; Caspase-3; CPP 32; CPP32; CPP32B; Cysteine protease CPP32
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
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