Mouse Anti-SERPINF1 Monoclonal Antibody (CBP2799)

Product Overview

Description

PEDF is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.

Expression Host

Mammalian cells

Immunogen

PEDF fusion protein Ag26660

Species Reactivity

Human; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2799

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

PEDF

Official Name

SERPINF1

Full Name

Serpin peptidase inhibitor, clade F

Alternative Names

Cell proliferation-inducing gene 35 protein;
EPC 1;
EPC-1;
EPC1;
OI12;
OI6;
PEDF;
PEDF_HUMAN;
PIG 35;
PIG35;

Gene ID

5176(Human)

Uniprot ID

P36955(Human)

References

1. Fu, X., Zhang, H., Chen, Z., Yang, Z., Shi, D., Liu, T.,... & Chen, M. (2019). TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathway. Cell death & disease, 10(6), 1-13.

Publications