Mouse Anti-CD133 Monoclonal Antibody (CBP2822)

Product Overview

Description

CD133 belongs to the prominin family. CD133 is a transmembrane glycoprotein with an NH2-terminal extracellular domain, five transmembrane loops and a cytoplasmic tail. The expression of CD133 has been reported in hematopoietic stem cells, endothelial progenitor cells, neuronal and glial stem cells, suggesting the potential role of CD133 as a cell surface marker of adult stem cells. CD133 has also been reported as a marker of cancer stem cells in various human tumors.

Expression Host

Mammalian cells

Immunogen

CD133 fusion protein Ag13327

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2822

Applications

FC; IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neurotransmission

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD133

Official Name

PROM1

Full Name

Prominin 1

Alternative Names

AC133; Antigen AC133; CD133; CORD12; MCDR2; MSTP061; PROM1; PROM1 1; PROM1 1; 2; 3; PROM1 1; 2; 3; 5; 7; PROM1

Gene ID

8842(Human)

Uniprot ID

O43490(Human)

References

1. Zhao, H., Yan, C., Hu, Y., Mu, L., Huang, K., Li, Q.,... & Qin, J. (2019). Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells. International journal of oncology, 54(3), 893-904. 2. Zhao, H., Wu, S., Li, H., Duan, Q., Zhang, Z., Shen, Q.,... & Yin, T. (2019). ROS/KRAS/AMPK signaling contributes to gemcitabine-induced stem-like cell properties in pancreatic cancer. Molecular Therapy-Oncolytics, 14, 299-312. 3. Wu, X., Wang, Y., Zhong, W., Cheng, H., & Tian, Z. (2020). RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 26, e921389-1.

Publications