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Creative Biolabs

Mouse Anti-NR4A2 Monoclonal Antibody (CBP2864)

[CAT#: NAB20101942CR]

Mouse Monoclonal (1H5B4) to NR4A2

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; ELISA

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Product Overview

Description

NR4A2 belongs to the orphan nuclear receptor (NR) family referred to as NR4A family, which have been implicated in cell cycle regulation, apoptosis, inflammation, metabolism and more recently in carcinogenesis [PMID:22583411]. NR4A2 also has a role in the expression of several proteins that are necessary for the synthesis and regulation of DA, such as tyrosine hidroxilase, DA transporter, vesicular monoamine transporter 2, and cRET [PMID:22294735]. Act as a transcriptional regulator, NR4A2 is essential for the differentiation and maintenance of meso-diencephalic mdDA neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.

Expression Host

Mammalian cells

Immunogen

NR4A2 fusion protein Ag1418

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2864

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Nurr1

Official Name

NR4A2

Full Name

Nuclear receptor subfamily 4, group A, member 2

Alternative Names

HZF 3; NOT; NR4A2; NURR1; Orphan nuclear receptor NURR1; RNR1; TINUR

Gene ID

4929(Human); 54278(Rat)

Uniprot ID

P43354(Human); Q07917(Rat)
Publications

Publications (0)

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