Mouse Anti-Human Clusterin Monoclonal Antibody (CBP3703)

Product Overview

Description

Clusterin, also known as Apolipoprotein J, is a heterodimeric glycoprotein that is a member of the heat-shock protein family. The protein exhibits a wide array of biological functions including clearance of cellular debris through chaperone activity, apoptosis, lipid transportation, cell clustering, and complement inhibition.

Immunogen

Recombinant human clusterin.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3703

Applications

WB; IHC-P

Application Notes

WB (0.2-1.0 µg/mL); IHC-P (1.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570

Product Properties

Form

Liquid

Formulation

50% glycerol in aqueous buffered solutions with preservatives.

Concentration

Batch Dependent

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon receipt, the antibody solution should be stored undiluted at-20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Clusterin

Official Name

CLU

Full Name

Clusterin

Alternative Names

CLU; Clusterin

Gene ID

1191(Human)

Uniprot ID

P10909(Human)

References

1. Trougakos IP. 2013. Gerontology 59:514. PubMed
2. Rizzi F, Bettuzzi S. 2010. Endocr. Relat. Cancer 17:R1. PubMed
3. Desikan RS, et al. 2014. JAMA Neurol. 71:180. PubMed
4. Carver JA, et al. 2003. IUBMB Life. 55:661. PubMed

Publications