Anti-REEP1 Monoclonal Antibody (CBP3839)

Product Overview

Description

Receptor expression enhancing protein 1 (REEP1) is a multi-pass mitochondrion membrane protein that is part of the DP1 family. REEP1 has been reported to interact and enhance the cell surface expression of odorant receptors. Interestingly, REEP1 mutations have been linked to neurodegenerative disorders of upper and lower motor neurons, hereditary spastic paraplegia (HSP), and distal hereditary motor neuropathy type V (dHMN-V).

Immunogen

Mouse recombinant protein fragment corresponding to amino acids 111-201.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP3839

Applications

Application Notes

WB (1.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

REEP1

Official Name

REEP1

Full Name

Receptor Accessory Protein 1

Alternative Names

Receptor Accessory Protein 1; Spastic Paraplegia 31 Protein; C2orf23; SPG31; Receptor Expression Enhancing Protein 1; Receptor Expression-Enhancing Protein 1; Chromosome 2 Open Reading Frame 23; HMN5B; Yip2a;