Product
Anti-CD45RB Monoclonal Antibody (CBP3850)
[CAT#: NAB2012373LS]
Anti-CD45RB Monoclonal Antibody [FITC]
- Host Species:
- Mouse
- Species Reactivity:
- Human; African green monkey; Baboon; Cynomolgus; Rhesus
- Applications:
- FC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
CD45RB is a 180-240 kD single chain type I membrane glycoprotein. CD45RB is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes.
Immunogen
Human thymocytes and T lymphocytes
Species Reactivity
Human; African green monkey; Baboon; Cynomolgus; Rhesus
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP3850
Applications
FC
Application Notes
FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
CD45
Official Name
PTPRC
Full Name
Protein tyrosine phosphatase, receptor type, C
Alternative Names
PTPRC; B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; protein tyrosine phosphatase; receptor type C; protein tyrosine phosphatase receptor type C
References
1. Lee KM, et al. 2014. Cell Transplant. 23:51.
2. Kamanaka M, et al. 2011. J. Exp. Med. 208:1027.
3. Gagliani N, et al. 2011. PLoS One 6(12):e28434.
4. Ten Hove T, et al. 2004. J. Leuko. Biol. 75:1010.
5. Ogilvy S, et al. 2003. J. Immunol. 171:1792.
2. Kamanaka M, et al. 2011. J. Exp. Med. 208:1027.
3. Gagliani N, et al. 2011. PLoS One 6(12):e28434.
4. Ten Hove T, et al. 2004. J. Leuko. Biol. 75:1010.
5. Ogilvy S, et al. 2003. J. Immunol. 171:1792.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
