Mouse Anti-Human SMN Monoclonal Antibody (CBP3980)
[CAT#: NAB2012925LS]
Anti-SMN Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
SMN1/Gem-associated protein 1 (Gemin 1) is a component of the survival of motor neurons (SMN) macromolecule protein complex, which plays an important role in the assembly and re-structuring of small nucleoproteins and transcriptosomes. The SMN complex localizes to the cytosol and nucleus of eukaryotic cells. SMN1 gene is nearly identical to the SMN2 gene, and both SMN1 and SMN2 encode the SMN protein. Mutations of SMN1 lead to spinal muscular atrophy.
Immunogen
Purified recombinant fragment of human SMN1 (amino acids 148-294) expressed in E. Coli.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3980
Applications
WB
Application Notes
WB (2.0- 10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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