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Creative Biolabs
Product

Mouse Anti-Human PPT1 Monoclonal Antibody (CBP3984)

[CAT#: NAB2012929LS]

Anti-PPT1 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB

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Product Overview

Description

PPT1 (Palmitoyl-protein thioesterase-1) was originally discovered as the enzyme that catalyzes polypeptide depalmitoylation. During lysosomal degradation, PPT1 removes the thioester-linked palmitic acid from the modified cysteine of targeted protein, which is important to palmitoylated protein degradation. Deficits in PPT1 have been identified as the leading cause of infantile neuronal ceroid liposuscinosis.

Immunogen

Recombinant protein corresponding to amino acids 100-306 of human PPT1.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3984

Applications

WB

Application Notes

WB (1.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

PPT1

Official Name

PPT1

Full Name

Palmitoyl-protein thioesterase 1

Alternative Names

PPT1; Palmitoyl-protein thioesterase 1

Gene ID

5538(Human); 19063(Mouse); 29411(Rat)

Uniprot ID

P50897(Human); O88531(Mouse); P45479(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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