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Creative Biolabs

Anti-Dicer Monoclonal Antibody (CBP4009)

[CAT#: NAB20121018LS]

Anti-Dicer Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB

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Product Overview

Description

Dicer, also known as double-strand-specific ribonuclease (DCR-1) and helicase with RNase motif (HERNA), processes double-stranded RNA and pre-microRNA (miRNA) to generate siRNA and miRNA, respectively. These short RNA sequences mediate RNA silencing through RISC (RNA-induced silencing complex).

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 1638-1899 of mouse Endoribonuclease Dicer.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4009

Applications

WB

Application Notes

WB (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Dicer

Official Name

DICER1

Full Name

Dicer

Alternative Names

DICER1; DCR1; Dicer; Dicer1e; HERNA; MNG1; RMSE2; K12H4.8-LIKE; dicer 1; ribonuclease III; GLOW

Gene ID

23405 (Human); 192119 (Mouse)

Uniprot ID

Q9UPY3 (Human); Q8R418 (Mouse)
Publications

Publications (0)

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