Mouse Anti-Human s100a5 Monoclonal Antibody (CBP4257)

Product Overview

Description

S100 calcium-binding protein A6 (S100A6) is a member of the S100 protein family, ubiquitously expressed in all cell types. S100A6 contains 2 EF-hand motives that bind to Calcium and enable the protein to function as a cellular Ca2+ sensor and regulator. By modulating Ca2+ signaling, S100A6 plays an important role in many physiological processes, including cell migration, process extension and cytoskeleton reorganization. S100A6 may also be involved in Ca2+-dependent insulin release and prolactin secretion.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP4257

Applications

Application Notes

WB (0.5-2.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

S100A5

Official Name

S100A5

Full Name

S100 Calcium Binding Protein A5

Alternative Names

S100 Calcium Binding Protein A5; S100 Calcium-Binding Protein A5; S100D; Protein S100-A5; Protein S-100D;

Gene ID

6276(Human); 20199(Mouse); 295211(Rat)

Uniprot ID

P33763(Human); P63084(Mouse); P63083(Rat)

References

1. Donato R, et al. 2017. Cell Mol Life Sci. 74(15):2749
2. Lesniak W, et al. 2017. Biol Chem. 398(10): 1087
3. Filipek A. 2006. Chemotherapy. 52(1):32

Publications