Mouse Anti-UBE2V1 Monoclonal Antibody (CBP4292)

[CAT#: NAB210162LS]

Anti-UBE2V1 Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human; Rat; Drosophila

Applications:: WB

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Product Overview

Description

Ubiquitination is a common post-translational modification of proteins and plays an important role in protein homeostasis. UBE2V1 encodes one of the ubiquitin-conjugating E2 enzyme variant proteins (UBE2V), which lacks the conserved cysteine residue required for the catalytic activity of E2s. Elevated expression of UBE2V1 has been associated with tumor development; however, it is not clear whether it functions as an oncogene or tumor suppressor gene. In addition, UBE2V1 is a key component in TRAF6 to control NF-κB activation.

Immunogen

Recombinant human UBE2V1 protein

Species Reactivity

Human; Rat; Drosophila

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP4292

Applications

Application Notes

WB (1.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.