Mouse Anti-TBL1 Monoclonal Antibody (CBP4351)
[CAT#: NAB2101133LS]
Anti-TBL1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
TBL1 is a protein that has sequence similarity with WD40 repeat-containing protein family. TBL1 plays an essential role in signal transduction, gene regulation, vesicle trafficking, and cytoskeletal arrangement through protein-protein interactions. TBL1 is also found as a component of nuclear receptor corepressor complexes through interaction with histone deacetylase 3, and is involved in Notch signaling. It is associated with diseases including ocular albinism and atrial septal defect 4.
Immunogen
Purified recombinant human TBL1 protein fragments expressed in E.coli.
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP4351
Applications
WB; IHC-P
Application Notes
WB (1.0 - 2.0 µg/mL); IHC-P (5.0 - 10.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
TBL1
Official Name
TBL1X
Full Name
Transducin (beta)-like 1X-linked
Alternative Names
TBL1X; EBI; SMAP55; TBL1; transducin (beta)-like 1X-linked; transducin beta like 1X-linked; transducin beta like 1 X-linked; CHNG8
References
1. Perissi V, et al. 2004. Cell. 116(4):511-26.
2. Li J, et al. 2008. Nat Cell Biol. 10(2):160-9.
2. Li J, et al. 2008. Nat Cell Biol. 10(2):160-9.
Publications
Publications (0)
Neural Cell Lines
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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