Rabbit Anti-CAMK2A/CAMK2B (CBP749)
CaMKII alpha / CaMKII beta (phospho T286) Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
inquiryImmunogen
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Formulation
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
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Storage
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes: avoid repeated freeze-thaw cycles.
Research Use Only
Target
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The product of the CAMK2A gene is an enzyme belonging to the serine/threonine-specific protein kinase family and the Ca2+/calmodulin-dependent protein kinase II subfamily. Ca2+ signal transduction is essential for several aspects of glutamatergic synaptic plasticity. The enzyme consists of four different chains: α; β; γ and δ. The alpha chain encoded by this gene is necessary for long-term hippocampus (LTP) and spatial learning. [Citation needed] In addition to its calcium-calmodulin (CaM)-dependent activity; the protein can also undergo autophosphorylation; resulting in CaM-independent activity. Two transcript variants encoding different isoforms have been identified for this gene.
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