NoGeneST™ Anti-tPA Aptamer, atPA aptamer

Name: NoGeneST™ Anti-tPA Aptamer, atPA aptamer
SKU: NRYF-0625-HZ118
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ118]

Aptamer designed to specifically recognize Tissue-Type Plasminogen Activator, a key enzyme in the fibrinolytic system used to dissolve blood clots.

Target:: tPA

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Product Overview

Relevant Diseases

Stroke

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

tPA

Full Name

Tissue-Type Plasminogen Activator

Gene ID

5327

Uniprot ID

P00750

Target Overview

Tissue-type plasminogen activator (tPA) is a serine protease that is a fundamental component of the fibrinolytic system, the body's mechanism for breaking down blood clots. The primary function of tPA is to convert the inactive zymogen, plasminogen, into its active form, plasmin. Plasmin is the enzyme that directly degrades the fibrin mesh that forms the structural foundation of a clot. Due to its potent clot-dissolving (thrombolytic) properties, recombinant tPA is used as a critical emergency medication for treating patients with ischemic stroke, myocardial infarction (heart attack), and pulmonary embolism.

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