NoGeneST™ HTT-ASO 1, Antisense Oligonucleotide

Name: NoGeneST™ HTT-ASO 1, Antisense Oligonucleotide
SKU: NRYF-0625-XY10
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-XY10]

Target:: HTT

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Product Overview

Description

HTT-ASO is an antisense oligonucleotide modified with phosphorothioate for enhanced stability and 2'-O-methoxyethyl (MOE) for improved target affinity. It targets Huntingtin protein (HTT) mRNA to rapidly inhibit HTT production.

Species

Human

Applications

Designed for Huntington's disease research, our HTT-ASO 1 specifically targets the Huntingtin (HTT) gene. By reducing the expression of mutant HTT protein, it helps researchers study its impact on neuronal survival, synaptic function, and the onset of neurodegeneration. Ideal for validating HTT as a therapeutic target and advancing preclinical drug development for Huntington's disease.

Relevant Diseases

Huntington's disease

Properties

Appearance

Solid

Shipping

Room temperature

Storage

Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).