NoGeneST™ TDP-43-ASO, Antisense Oligonucleotide

Name: NoGeneST™ TDP-43-ASO, Antisense Oligonucleotide
SKU: NRYF-0625-XY78
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-XY78]

Target:: TDP-43

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Product Overview

Description

TDP-43-ASO is designed to target specific regions of TDP-43 mRNA, preventing its translation into protein, or to correct mis-splicing of RNA transcripts that lead to dysregulation of TDP-43 function.

Species

Human

Applications

Reduces TDP-43 expression to investigate its role in RNA processing, protein aggregation, and motor neuron degeneration in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Suitable for in vitro (motor neuron cultures) and in vivo (ALS mouse models) studies.

Relevant Diseases

Amyotrophic Lateral Sclerosis

Properties

Appearance

Solid

Shipping

Room temperature

Storage

Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).