FITC-Labeled Human Amyloid Beta 1-42 Wild Type Pre-formed Fibrils (PFFs) for Alzheimer's Disease Imaging Studies

Name: FITC-Labeled Human Amyloid Beta 1-42 Wild Type Pre-formed Fibrils (PFFs) for Alzheimer's Disease Imaging Studies
SKU: NRYF-0826-CW108
Rating: 5 (1 reviews)

[CAT#: NRYF-0826-CW108]

Species:: Human

Expression System:: E,coli

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Product Overview

Description

A recombinant human amyloid-β 1-42 pre-formed fibril preparation designed for Alzheimer's Disease Imaging studies.

Species

Human

Protein Length

42 aa

Applications

EM; FuncS; SDS-PAGE; MS; BI; Live-cell imaging

Conjugates

FITC

Molecular Weight

4.51 kDa (Aβ1-42 monomer)

Target

Target Protein

Amyloid Beta

Synonym

Aβ; Beta-Amyloid; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma; alpha-sAPP

Research Areas

Neurodegeneration; Protein Aggregation; Alzheimer's Disease

Introduction

Amyloid beta 1-42 aggregation and plaque deposition are defining pathological features of Alzheimer's disease and are associated with progressive synaptic and neuronal dysfunction. This product contains FITC-labeled wild-type human amyloid beta 1-42 pre-formed fibrils for imaging cellular uptake, localization, and amyloid deposition. For research use only.

Gene ID

351

Uniprot ID

P05067

Properties

Buffer

20 mM Tris, 150 mM NaCl, pH7.4

Storage

-80°C

Shipping

Dry ice

Quality Control

Transmission electron microscopy (TEM) confirms uniform fibrillar morphology; Thioflavin T (ThT) assay verifies robust β-sheet-rich aggregation; mass spectrometry confirms high purity and expected molecular species profile.

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