Human GSK-3beta (pS9 / Total) ELISA Kit [Colorimetric]
[CAT#: NPP2011ZP70]
- Applications:
- ELISA
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Product Overview
Description
ELISA (enzyme-linked immunosorbent assay) kit is used for semi-quantitative determination of GSK-3 protein (pS9) and total GSK-3 protein (Total) in human and mouse cells. Glycogen synthase kinase-3 (GSK3) was originally identified as an enzyme that phosphorylates and inactivates glycogen synthase in response to insulin to regulate glycogen synthesis. GSK3 is expressed as GSK3A and GSK3B, two closely related and similarly regulated isoforms. It is known that GSK3B participates in a variety of cell signal transduction processes, including glycogen synthesis, cell adhesion, and is related to Alzheimer's disease. GSK3B is an important element of PI3 kinase/Akt signaling pathway, and its kinase activity is down-regulated by Akt-mediated phosphorylation of Ser9.
Species Reactivity
Human
Applications
ELISA
Research Areas
Neural Signal Transduction
Pathways
Notch Pathway
Properites
Sensitivity
In most cases, the sensitivity is below 5 µg/ml.
Platform
Microplate
Detection Method
Colorimetric
Sample Type
Cell culture extracts, Cell Lysate
Assay Type
Semi-quantitative
Assay Time
1h 30m
Preparation and Storage
Storage
Store at +4°C. Please refer to protocols.
Research Use Only
For research use only
Target Details
Publications
Publications (0)
Neural Antibodies
Kits
Case Studies
For Research Use Only. Not For Clinical Use.
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