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Creative Biolabs

Human GSK-3beta (pS9 / Total) ELISA Kit [Colorimetric]

[CAT#: NPP2011ZP70]

Applications:
ELISA

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Product Overview

Description

ELISA (enzyme-linked immunosorbent assay) kit is used for semi-quantitative determination of GSK-3 protein (pS9) and total GSK-3 protein (Total) in human and mouse cells. Glycogen synthase kinase-3 (GSK3) was originally identified as an enzyme that phosphorylates and inactivates glycogen synthase in response to insulin to regulate glycogen synthesis. GSK3 is expressed as GSK3A and GSK3B, two closely related and similarly regulated isoforms. It is known that GSK3B participates in a variety of cell signal transduction processes, including glycogen synthesis, cell adhesion, and is related to Alzheimer's disease. GSK3B is an important element of PI3 kinase/Akt signaling pathway, and its kinase activity is down-regulated by Akt-mediated phosphorylation of Ser9.

Species Reactivity

Human

Applications

ELISA

Research Areas

Neural Signal Transduction

Pathways

Notch Pathway
Properites

Sensitivity

In most cases, the sensitivity is below 5 µg/ml.

Platform

Microplate

Detection Method

Colorimetric

Sample Type

Cell culture extracts, Cell Lysate

Assay Type

Semi-quantitative

Assay Time

1h 30m
Preparation and Storage

Storage

Store at +4°C. Please refer to protocols.

Research Use Only

For research use only
Target Details

Target

GSK3 Beta

Official Name

GSK3B

Full Name

glycogen synthase kinase 3 beta

Alternative Names

EC 2.7.11.26; EC 2.7.11.1; GSK-3 beta; Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B

Gene ID

2932(Human);56637(Mouse)

Uniprot ID

P49841(Human);Q9WV60(Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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