iNeu™ Human Astrocytes for Mitochondrial Sensor Assay

[CAT#: NCL-2103-P60]

Positive for GFAP and S100β

Species:: Human

Applications:: Mitochondrial Sensor Assay

Cell Types:: Astrocytes

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Product Overview

Description

Astrocytes constitute 20-40% of the total number of cells in the mammalian brain. Mitochondria are highly dynamic organelles with a plethora of functions, including regulation of calcium homeostasis, energy metabolism, and inflammatory activation. Scientists found that mitochondrial dysfunction in astrocytes is related with may CNS diseases such as Alzheimer's disease and Parkinson's disease.

iNeu™ Human Astrocytes for Mitochondrial Sensor Assay from Creative Biolabs are derived from human iPSCs and expresses typical astrocyte markers (GFAP and S100β). Besides, we introduce mitochondria sensors into those cells, which respond to mitochondrial calcium changes in the 605nm-625nm fluorescent range. NCL-2103-P60 is useful in vitro model for uncovering the mechanisms of astrocyte mitochondrial dysfunction in CNS diseases.

Features

Positive for GFAP and S100β;
Drug discovery and toxicology screening

Cell Types

Astrocytes

Applications

Mitochondrial Sensor Assay

Species

Human

Properties

Size

0.5-1M cells/vial

Growth Pattern

Adherent

Shipping

Dry ice

Storage

Liquid Nitrogen

Handling Advice

Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep
the cells in liquid nitrogen until they are needed for experiments.