Product
NeuroMab™ Mouse Anti-Beta Amyloid (CBP1930)
[CAT#: NAB2007FY356]
Mouse Monoclonal [DE2B4] to Beta Amyloid (aa1-17)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; IF; IHC-P; IP
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-human beta amyloid antibody, clone DE2B4 recognizes human beta amyloid peptide, which is the main protein component of the amyloid core in neural plaques.
In immunohistology, the antibody can detect extracellular amyloid β with senile plaques and vascular amyloid in the brain of Alzheimer's disease.
In immunohistology, the antibody can detect extracellular amyloid β with senile plaques and vascular amyloid in the brain of Alzheimer's disease.
Immunogen
A synthetic peptide composed of residues 1-17 of amyloid beta protein.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1930
Applications
ELISA; IF; IHC-P; IP
Relevant Diseases
Alzheimer's Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1570
Product Properties
Form
Liquid
Formulation
PBS; 0.09% Sodium Azide
Preservatives
Yes
Concentration
1.0 mg/ml
Purification
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Lee, M.H. et al. (2010) TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
2. Chang, J.Y. et al. (2012) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death.
3. Koronyo-Hamaoui, M. et al. (2011) Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.
2. Chang, J.Y. et al. (2012) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death.
3. Koronyo-Hamaoui, M. et al. (2011) Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
