Product
Rat Anti-LRP8 Monoclonal Antibody (CBP2486)
[CAT#: NAB2010608LS]
Anti LRP8 Monoclonal Antibody
- Host Species:
- Rat
- Species Reactivity:
- Human; Mouse
- Applications:
- WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
LDL Receptor Related Protein 8 (LRP8), also known as ApoER2, is a receptor for members of low-density lipoproteins. LRP8 interacts with its ligand reelin, and triggers reelin signaling to regulate cellular processes such as neuronal cell migration and long-term potentiation of mature neurons. LRP8 also interacts with and downregulates APP endocytosis. This interactions leads to increased amyloid beta production, demonstrating a major role for LRP8 in the pathogenesis of Alzheimer's disease.
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG2a, κ
Clone Number
CBP2486
Applications
WB
Application Notes
WB (2-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C.
Handling Advice
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
LRP8
Official Name
LRP8
Full Name
Low-density lipoprotein receptor-related protein 8
Alternative Names
LRP8; APOER2; HSZ75190; LRP-8; MCI1; low density lipoprotein receptor-related protein 8; LDL receptor related protein 8
Publications
Publications (0)
Neural Genes
Neural Antibodies
For Research Use Only. Not For Clinical Use.
