Mouse Anti-HDAC4 Monoclonal Antibody (CBP2858)

[CAT#: NAB20101936CR]

Mouse Monoclonal (1D2G12) to HDAC4

Host Species:: Mouse

Species Reactivity:: Human; Rat; Mouse

Applications:: WB; ELISA

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Product Overview

Description

HDAC4 belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Expression Host

Mammalian cells

Immunogen

HDAC4 fusion protein Ag11345

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2858

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

HDAC4

Official Name

HDAC4

Full Name

Histone deacetylase 4

Alternative Names

HA6116; HD4; HDAC A; HDAC4; HDACA; histone deacetylase 4; KIAA0288

Gene ID

9759(Human); 208727(Mouse)

Uniprot ID

P56524(Human); Q6NZM9(Mouse)

References

1. Zhan, W., Liao, X., Liu, J., Tian, T., Yu, L., & Li, R. (2020). USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3. Oncogenesis, 9(5), 1-14.

Publications