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Creative Biolabs

Mouse Anti-EIF4G1 Monoclonal Antibody (CBP2925)

[CAT#: NAB20102003CR]

Mouse Monoclonal (2B10G8) to EIF4G1

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IF; WB; ELISA

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Product Overview

Description

Eukaryotic cellular messenger RNAs are posttranscriptionally modified by addition of an m(7)GTP moiety to the 5-prime terminus, referred to as a cap. Recognition of the cap structure and unwinding of mRNA secondary structure during the initiation phase of protein synthesis is catalyzed by initiation factors of the eIF4 group. EIF4G1, a subunit of eIF4 gamma, forms various complexes with the other eIF4 polypeptides. Mutations in the EIF4G1 gene, encoding a component of the eIF4F translation initiation complex, were recently reported as a possible cause for the autosomal dominant form of Parkinson's disease.

Expression Host

Mammalian cells

Immunogen

EIF4G1 fusion protein Ag8357

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2925

Applications

IF; WB; ELISA

Application Notes

IF : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

500 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

EIF4G1

Official Name

EIF4G1

Full Name

Eukaryotic translation initiation factor 4 gamma, 1

Alternative Names

DKFZp686A1451; eIF 4 gamma 1; eIF 4G 1; eIF 4G1; EIF4F; EIF4G; EIF4G1; EIF4GI; p220

Gene ID

1981(Human); 208643(Mouse); 287986(Rat)

Uniprot ID

Q04637(Human); Q6NZJ6(Mouse); Q4G001(Rat)
Publications

Publications (0)

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