Mouse Anti-TUBA1B Monoclonal Antibody (CBP3014)

Product Overview

Description

Alpha-tubulin belongs to a large superfamily of tubulin proteins. There are a number of different subtypes that have a molecular weight of ~50kDa and are able to bind to beta-tubulin, forming a heterodimer that polymerizes to microtubules as part of the cytoskeleton. These maintain cell structure, provide platforms for intracellular transport, and are also involved in cell division.

Expression Host

Mammalian cells

Immunogen

Recombinant Protein

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP3014

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neural Cell

Conjugation

HRP

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

2000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

TUBA1B

Official Name

TUBA1B

Full Name

Tubulin, alpha 1b

Alternative Names

alpha Tubulin; Alpha tubulin ubiquitous; TUBA1B; tubulin; Tubulin alpha; tubulin; alpha 1b; α-tubulin

Gene ID

10376(Human); 22143(Mouse); 500929(Rat)

Uniprot ID

P68363(Human); P05213(Mouse); Q6P9V9(Rat)

References

1. Simmons, A. J., Park, R., Sterling, N. A., Jang, M. H., van Deursen, J. M., Yen, T. J.,... & Kim, S. (2019). Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death. Human molecular genetics, 28(11), 1822-1836. 2. Liu, J., Yuan, Y., Xu, J., Xiao, K., Xu, Y., Guo, T.,... & Zheng, H. (2018). β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling. Frontiers in Immunology, 9, 2930. 3. Chang, C. H., Zanini, M., Shirvani, H., Cheng, J. S., Yu, H., Feng, C. H.,... & Cigna, S. M. (2019). Atoh1 controls primary cilia formation to allow for SHH-triggered granule neuron progenitor proliferation. Developmental Cell, 48(2), 184-199.

Publications